• Environmental genomics of Late Pleistocene black bears and giant short-faced bears 

      Pedersen, Mikkel W.; De Sanctis, Bianca; Saremi, Nedda F.; Sikora, Martin; Puckett, Emily E.; Gu, Zhenquan; Moon, Katherine L.; Kapp, Joshua D.; Vinner, Lasse; Vardanyan, Zaruhi; Ardelean, Ciprian F.; Arroyo-Cabrales, Joaquin; Cahill, James A.; Heintzman, Peter D.; Zazula, Grant D.; MacPhee, Ross D. E.; Shapiro, Beth; Durbin, Richard; Willerslev, Eske (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-19)
      Analysis of ancient environmental DNA (eDNA) has revolutionized our ability to describe biological communities in space and time,1, 2, 3 by allowing for parallel sequencing of DNA from all trophic levels.4, 5, 6, 7, 8 However, because environmental samples contain sparse and fragmented data from multiple individuals, and often contain closely related species,9 the field of ancient eDNA has so far ...
    • Genomic Evidence of Widespread Admixture from Polar Bears into Brown Bears during the Last Ice Age 

      Cahill, James A.; Heintzman, Peter D.; Harris, Kelley; Teasdale, Matthew D.; Kapp, Joshua D.; Soares, Andre, E. R.; Stirling, Ian; Bradley, Daniel; Edwards, Ceiridwen J.; Graim, Kiley; Kisleika, Aliaksandr A.; Malev, Alexander V.; Monaghan, Nigel; Green, Richard E.; Shapiro, Beth (Journal article; Tidsskriftartikkel, 2018-02-20)
      Recent genomic analyses have provided substantial evidence for past periods of gene flow from polar bears (<i>Ursus maritimus</i>) into Alaskan brown bears (<i>Ursus arctos</i>), with some analyses suggesting a link between climate change and genomic introgression. However, because it has mainly been possible to sample bears from the present day, the timing, frequency, and evolutionary significance ...
    • Natural selection shaped the rise and fall of passenger pigeon genomic diversity 

      Murray, Gemma G.R.; Soares, André E.R.; Novak, Ben J.; Schaefer, Nathan K.; Cahill, James A.; Baker, Allan J.; Demboski, John R.; Doll, Andrew; Da Fonseca, Rute R.; Fulton, Tara L.; Gilbert, Marcus Thomas Pius; Heintzman, Peter D.; Letts, Brandon; McIntosh, George; O'Connell, Brendan L.; Peck, Mark; Pipes, Marie-Lorraine; Rice, Edward S.; Santos, Kathryn M.; Sohrweide, A. Gregory; Vohr, Samuel H.; Corbett-Detig, Russell B.; Green, Richard E.; Shapiro, Beth (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-17)
      The extinct passenger pigeon was once the most abundant bird in North America, and possibly the world. Although theory predicts that large populations will be more genetically diverse, passenger pigeon genetic diversity was surprisingly low. To investigate this disconnect, we analyzed 41 mitochondrial and 4 nuclear genomes from passenger pigeons and 2 genomes from band-tailed pigeons, which are ...
    • A new genus of horse from Pleistocene North America 

      Heintzman, Peter D.; Zazula, Grant D.; MacPhee, Ross D. E.; Scott, Eric; Cahill, James A.; McHorse, Brianna K.; Kapp, Joshua D.; Stiller, Mathias; Wooller, Matthew J.; Orlando, Ludovic; Southon, John R.; Froese, Duane G.; Shapiro, Beth (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-28)
      The extinct ‘New World stilt-legged’, or NWSL, equids constitute a perplexing group of Pleistocene horses endemic to North America. Their slender distal limb bones resemble those of Asiatic asses, such as the Persian onager. Previous palaeogenetic studies, however, have suggested a closer relationship to caballine horses than to Asiatic asses. Here, we report complete mitochondrial and partial nuclear ...